Dental age estimation in children with chromosomal syndromes
When the age of an individual is unknown, age assessment
refers to the procedures through which authorities try to
establish the chronological age of an individual. Dental
evidence demonstrated to be very effective in estimating age
and dental mineralization is largely deemed a process scarcely
influenced by major diseases and nutritional or environmental
factors which can affect child growth. This research aims to
understand the possible influence of genetic syndromes on
dental maturation of affected individuals.
The sample is composed of a test sample of 159 chromosomal
affected children, 69 males and 90 females, and a control
sample of 157 healthy children, 77 males and 80 females aged
between 4,49 and 19,8years. London Atlas was applied to
estimate dental age on OPGs (orthopantompographies).
No statistical significant difference has been found in dental
estimates between syndromic and healthy individuals.
Moreover no statistical significant difference emerged between
sexes and age cohorts. Children affected by Down or Williams
syndromes nor mean error neither the mean accuracy per
cohort of age show differences compared to non-affected
The London Atlas can be validly applied to age estimation of
individuals with multiple agenesis as in Down and Williams
syndromes, even if it a slight overestimation of age occurs
systematically in syndromic as well as in healthy samples. The
current findings suggest that dental maturation is a very stable
biological process scarcely affected by even serious illnesses as
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